The OUHSC Clinical Research Informatics team is leading the deployment of OnCore to facilitate the integration of research infrastructure and provide critical functionality, to include protocol, subject, financial, and biospecimen tracking, for the full spectrum of clinical trials and research performed within the organization. OnCore is used by more than 130 academic medical and cancer centers as well as healthcare systems and therefore considered the industry gold standard for clinical trial management systems (CTMS). It provides a centralized, comprehensive system for managing the full life cycle of a clinical trial. OnCore is a secure, web-based application compliant with applicable laws and regulations.  

The University of Oklahoma Health Sciences Center commenced OnCore implementation planning in May 2021 and will begin a phased go-live in 2022.  



  • Protocol Management: define staff roles, record sponsor information, treatment and disease details, participating institutions, study sites, and affiliates, document committee reviews, store consent forms, and perform general task management.
  • Subject Administration: registration, eligibility verification, enrollment documentation, and status management. 
  • Biospecimen Management: record collection details, management of specimen inventory, track both banking and correlative protocols, and designation of parent/child specimens.
  • Financial Management: centralized storage of the research charge master, budget creation, sponsor invoicing, receipt tracking, and payment reconciliation. 
  • Subject Administration: registration, eligibility verification, enrollment documentation, and status management.



  • Protection of subjects 
  • Facilitation of remote monitoring 
  • Improved compliance 
  • Streamlined research data management 
  • Standardized user training 
  • Accurate institutional metrics 
  • Custom reporting features 
  • Access logs and audit trails 
  • Efficient program and resource management 
  • Centralized research portfolio 

System Support Links


Stephenson Cancer Center 

SCC CTO Website

SCC Employee Access Form

SCC CTO Monitor Instructions

Clinical Trials Startup