Our Mission

Established in 2013, the Oklahoma Clinical and Translational Science Institute serves as a catalyst for clinical and translational research that improves health and healthcare for underserved and underrepresented populations, to provide training and infrastructure to help junior investigators to launch independent research careers, and to expand the opportunities of IDeA states and Oklahoma communities to participate in research that improves the health of our residents.

Oklahoma Shared Clinical and Translational Resources

OSCTR is Oklahoma's NIH-funded IDeA-CTR that provides resources, information, and training to help individuals or communities involved in performing clinical and translational research in the state

Oklahoma Primary Healthcare Improvement Cooperative

OPHIC is the implementation science arm of a statewide network to help improve healthcare delivery assisting primary care practices to adopt evidence-based best practices for the care of their patients.

OCTSI Clinical Research Unit

The OCTSI CRU assists medical providers to identify and conduct clinical research opportunities in Oklahoma.

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Recent Publications

Assessing the effect of selective serotonin reuptake inhibitors in the prevention of post-acute sequelae of COVID-19

Read more about Assessing the effect of selective serotonin reuptake inhibitors in the prevention of post-acute sequelae of COVID-19

Comput Struct Biotechnol J. 2024 Jan 9;24:115-125. doi: 10.1016/j.csbj.2023.12.045. eCollection 2024 Dec.

ABSTRACT

BACKGROUND: Post-acute sequelae of COVID-19 (PASC) produce significant morbidity, prompting evaluation of interventions that might lower risk. Selective serotonin reuptake inhibitors (SSRIs) potentially could modulate risk of PASC via their central, hypothesized immunomodulatory, and/or antiplatelet properties although clinical trial data are lacking.

Impaired Neurovascular Coupling and Increased Functional Connectivity in the Frontal Cortex Predict Age-Related Cognitive Dysfunction

Read more about Impaired Neurovascular Coupling and Increased Functional Connectivity in the Frontal Cortex Predict Age-Related Cognitive Dysfunction

Adv Sci (Weinh). 2023 Dec 28:e2303516. doi: 10.1002/advs.202303516. Online ahead of print.

ABSTRACT

SARS-CoV-2 Infection is Associated with an Increase in New Diagnoses of Schizophrenia Spectrum and Psychotic Disorder: A Study Using the US National COVID Cohort Collaborative (N3C)

Read more about SARS-CoV-2 Infection is Associated with an Increase in New Diagnoses of Schizophrenia Spectrum and Psychotic Disorder: A Study Using the US National COVID Cohort Collaborative (N3C)

medRxiv. 2023 Dec 5:2023.12.05.23299473. doi: 10.1101/2023.12.05.23299473. Preprint.

ABSTRACT

Automatic renal carcinoma biopsy guidance using forward-viewing endoscopic optical coherence tomography and deep learning

Read more about Automatic renal carcinoma biopsy guidance using forward-viewing endoscopic optical coherence tomography and deep learning

Res Sq. 2023 Nov 23:rs.3.rs-3592809. doi: 10.21203/rs.3.rs-3592809/v1. Preprint.

ABSTRACT

Scale-Free Functional Brain Networks Exhibit Increased Connectivity, Are More Integrated and Less Segregated in Patients with Parkinson's Disease following Dopaminergic Treatment

Read more about Scale-Free Functional Brain Networks Exhibit Increased Connectivity, Are More Integrated and Less Segregated in Patients with Parkinson's Disease following Dopaminergic Treatment

Fractal Fract. 2022 Dec;6(12):737. doi: 10.3390/fractalfract6120737. Epub 2022 Dec 13.

ABSTRACT

Oklahoma Shared Clinical and Translational Resources

Developing investigators

Engaging communities

Our Mission

Oklahoma Shared Clinical and Translational Resources

Oklahoma Primary Healthcare Improvement Cooperative

OCTSI Clinical Research Unit

Recent Publications

Assessing the effect of selective serotonin reuptake inhibitors in the prevention of post-acute sequelae of COVID-19

Impaired Neurovascular Coupling and Increased Functional Connectivity in the Frontal Cortex Predict Age-Related Cognitive Dysfunction

SARS-CoV-2 Infection is Associated with an Increase in New Diagnoses of Schizophrenia Spectrum and Psychotic Disorder: A Study Using the US National COVID Cohort Collaborative (N3C)

Automatic renal carcinoma biopsy guidance using forward-viewing endoscopic optical coherence tomography and deep learning

Scale-Free Functional Brain Networks Exhibit Increased Connectivity, Are More Integrated and Less Segregated in Patients with Parkinson's Disease following Dopaminergic Treatment

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Hope is Her Name: From STRONG Scholar to Future Pharmacist

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