Our Mission

Established in 2013, the Oklahoma Clinical and Translational Science Institute serves as a catalyst for clinical and translational research that improves health and healthcare for Oklahomans, to provide training and infrastructure to help junior investigators to launch independent research careers, and to expand the opportunities of IDeA states and Oklahoma communities to participate in research that improves the health of our residents. 

Oklahoma Shared Clinical and Translational Resources

OSCTR is Oklahoma's NIH-funded IDeA-CTR that provides resources, information, and training to help individuals or communities involved in performing clinical and translational research in the state

Oklahoma Primary Healthcare Improvement Cooperative

 

OPHIC is the implementation science arm of a statewide network to help improve healthcare delivery assisting primary care practices to adopt evidence-based best practices for the care of their patients.

OCTSI Clinical Research Unit

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The OCTSI CRU assists medical providers to identify and conduct clinical research opportunities in Oklahoma.

OCTSI receives $15 million grant to improve heart health in Oklahoma

OCTSI receives $15 million grant to improve heart health in Oklahoma

Researchers with the University of Oklahoma in Tulsa and Oklahoma City have received a $15 million grant to improve heart health in residents throughout the state.

OU is one of seven grantees in the nation for the award from the U.S. Department of Health and Human Services.

OSCTR Clinical Resources Space Availability

We would like all clinical investigators within our Oklahoma Shared Clinical and Translational Resources partner institutions to be aware that the OSCTR Clinical Research space in the Harold Hamm Diabetes Center is now open and available for your clinical research studies. We have a new clinical research coordinator, Janice Gales, who looks forward to aiding investigators with clinical research projects and regulatory assistance. Janice is a registered nurse who has been involved in clinical research on campus since 1995. 

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Recent Publications

Vitamin D Deficiency and Cardiovascular Disease Risk Factors Among American Indian Adolescents: The Strong Heart Family Study

Prev Chronic Dis. 2025 Apr 3;22:E13. doi: 10.5888/pcd22.240354.

ABSTRACT

INTRODUCTION: We aimed to describe the prevalence of vitamin D deficiency among American Indian adolescents and determine its association with cardiovascular disease (CVD) risk factors.

Multi-level determinants of vaccination of the American Indian and Alaska Native population: a comprehensive overview

Front Public Health. 2025 Feb 18;13:1490286. doi: 10.3389/fpubh.2025.1490286. eCollection 2025.

ABSTRACT

CONTEXT: American Indians and Alaska Natives (AIANs) are historically disadvantaged, losing 20 million (95%) of their population largely through epidemics since 1,520 and continuing lower overall vaccination coverage than other races. Determinants of this lower coverage are underexamined.

Effect of Early and Delayed Treatment With Remdesivir on Mortality in Patients Hospitalized With COVID-19

Open Forum Infect Dis. 2025 Feb 27;12(2):ofae740. doi: 10.1093/ofid/ofae740. eCollection 2025 Feb.

ABSTRACT

BACKGROUND: We applied a target trial emulation framework to estimate the association between early and delayed initiation of remdesivir (RDV) with mortality in hospitalized adults between May 1, 2020, and July 31, 2024, with varying coronavirus disease 2019 (COVID-19) clinical severity.

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