Our Mission

Established in 2013, the Oklahoma Clinical and Translational Science Institute serves as a catalyst for clinical and translational research that improves health and healthcare for underserved and underrepresented populations, to provide training and infrastructure to help junior investigators to launch independent research careers, and to expand the opportunities of IDeA states and Oklahoma communities to participate in research that improves the health of our residents. 

Oklahoma Shared Clinical and Translational Resources

OSCTR is Oklahoma's NIH-funded IDeA-CTR that provides resources, information, and training to help individuals or communities involved in performing clinical and translational research in the state

Oklahoma Primary Healthcare Improvement Cooperative

 

OPHIC is the implementation science arm of a statewide network to help improve healthcare delivery assisting primary care practices to adopt evidence-based best practices for the care of their patients.

OCTSI Clinical Research Unit

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The OCTSI CRU assists medical providers to identify and conduct clinical research opportunities in Oklahoma.

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EvidenceNOW Grant Initiative Provides Support for Primary Care Practices in Oklahoma to Advance Cardiovascular Care

Submitted by Anonymous (not verified) on

Heart disease remains the number one cause of death in the United States, claiming more lives than all cancers combined. Heart disease is also taking a toll on Oklahoma. But the evidence is clear—we can reduce the threat by applying the ABCS of cardiovascular disease prevention: Aspirin use by high-risk individuals, Blood pressure control, Cholesterol management, and Smoking cessation.

OCTSI receives $15 million grant to improve heart health in Oklahoma

Submitted by Anonymous (not verified) on

OCTSI receives $15 million grant to improve heart health in Oklahoma

Researchers with the University of Oklahoma in Tulsa and Oklahoma City have received a $15 million grant to improve heart health in residents throughout the state.

OU is one of seven grantees in the nation for the award from the U.S. Department of Health and Human Services.

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Recent Publications

Sex-specific effects of injury and beta-adrenergic activation on metabolic and inflammatory mediators in a murine model of post-traumatic osteoarthritis

Osteoarthritis Cartilage. 2024 Sep;32(9):1097-1112. doi: 10.1016/j.joca.2024.03.109. Epub 2024 Mar 26.

ABSTRACT

OBJECTIVE: Metabolic processes are intricately linked to the resolution of innate inflammation and tissue repair, two critical steps for treating post-traumatic osteoarthritis (PTOA). Based on lipolytic and immunoregulatory actions of norepinephrine, we hypothesized that intra-articular β-adrenergic receptor (βAR) stimulation would suppress PTOA-associated inflammation in the infrapatellar fat pad (IFP) and synovium.

Longitudinal detection of gait alterations associated with hypertension-induced cerebral microhemorrhages in mice: predictive role of stride length and stride time asymmetry and increased gait entropy

Geroscience. 2024 Jun 25. doi: 10.1007/s11357-024-01210-3. Online ahead of print.

ABSTRACT

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